目的 采用计算流体力学数值模拟方法对颈动脉支架植入术（CAS）治疗颈动脉狭窄的效果进行评估。方法 采用Mimics软件对1例颈动脉狭窄患者手术前后的CT影像进行三维重建，构建个体化颈动脉分叉模型，利用计算流体力学方法对模型进行三维流动数值模拟计算，以壁面剪切应力、壁面压力、血流轨迹和流量等血流动力学指标对CAS的疗效进行评估。结果 数值模拟计算结果显示：与术前比较，CAS术后颈动脉内的流动速度、颈内与颈外动脉的流量分配比例、壁面剪切力和壁面压力等血流动力学指标发生明显变化，血液流动状态明显改善。结论 计算流体力学数值模拟评估CAS的效果更为直观且合理，并能够在术前为个体病例提供最优的指导性方案。

Objective To evaluate the therapeutic effect of carotid artery stenting (CAS) on carotid artery stenosis with computational fluid dynamics. Methods Three-dimensional reconstruction of CT images before and after operation was conducted with Mimics software in one patient with carotid artery stenosis. Individualized carotid artery bifurcation model was constructed, and computational fluid dynamics was employed to perform three-dimensional fluid numerical simulation calculation. The therapeutic effect of CAS was evaluated with hemodynamic parameters of wall shear stress, wall pressure, blood flow tract and blood volume. Results Numerical simulation calculation indicated that compared with those before operation, there were significant changes in carotid blood flow velocity, blood flow distribution between internal carotid artery and external carotid artery, wall shear stress and wall pressure, and the blood flow state was significantly improved. Conclusion Computational fluid dynamics numerical simulation is rational in evaluation of therapeutic effect of CAS, and can provide individualized optimal guidance before operation.