神经病理性疼痛属于慢性疼痛中的一种，近年来，因其发病机制的复杂性和临床治疗的低治愈率日益受到广大学者的关注。大量研究表明，神经损伤后，大量细胞因子被释放，开启体内多条信号通路，参与疼痛的形成。文章旨在探讨Neuregulin1/erbB信号在神经病理性疼痛中的作用。

Neuropathic pain is a common chronic pain, and has received more attention recently due to its complicated pathogenesis and ineffective treatment. Many studies have found that a number of cytokines and multiple signaling pathways are involved in the pain procession after never injury. The role of Neuregulin1/erB signaling pathway in neuropathic pain is discussed in this paper.