Abstract:

Objective To observe the effect of band-type chest compression device on cardiopulmonary resuscitation (CPR) in pig model of cardiac arrest by comparison with manual chest compression. Methods Twenty-six pigs were randomly divided into mechanical chest compression group (n=13) and conventional manual chest compression group (n=13), and mechanical chest compression and manual chest compression were performed respectively 4 min after cardiac arrest induced by ventricular fibrillation. The survival rates after CPR were determined, the hemodynamic parameters, blood gas of aorta and lactate concentrations before ventricular fibrillation and 1 min, 5 min and 1 h after return of spontaneous circulation (ROSC) were measured, and the injury of ribs after successful CRP was examined with X-ray radiography. Results There was no significant difference in survival rates at ROSC and 1 h after CPR between two groups (P>0.05). The aortic systolic pressure, aortic diastolic pressure and mean aortic pressure 1 min after ROSC in conventional manual chest compression group were significantly higher than those in mechanical chest compression group (P<0.05), while there was no significant difference in coronary perfusion pressure at different time points between two groups (P>0.05). The lactate concentrations 1 min, 15 min and 1 h after ROSC in mechanical chest compression group were significantly lower than those in conventional manual chest compression group (P<0.05). X-ray radiography revealed there was no significant difference in the injury rates of ribs between mechanical chest compression group and conventional manual chest compression group (33.3% vs 45.5%, P>0.05). Conclusion Band-type chest compression device may yield similar effect of CPR in pigs with conventional manual chest compression, and band-type chest compression device can be a substitute for manual compression in CPR.

Key words: band-type thoracic compression device, ventricular fibrillation model, conventional manual compression, hemodynamics