›› 2012, Vol. 32 ›› Issue (5): 610-.doi: 10.3969/j.issn.1674-8115.2012.05.017

• Original article (Clinical research) • Previous Articles     Next Articles

Role of 18F-FDG PET/CT whole body scan in diagnosis of small bowel tumors

HU Jia-jia1, WANG Zheng-ting2, ZHONG Jie2, LIANG Sheng1, ZHANG Miao1, LI Biao1   

  1. 1.Department of Nuclear Medicine, 2.Department of Gastroenterology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Online:2012-05-28 Published:2012-06-01
  • Supported by:

    Shanghai Leading Academic Discipline Project, S30203;Shanghai Research Foundation for Cultivation of Outstanding Young Teachers in Colleges, jdy09096

Abstract:

Objective To investigate the value of 18F-FDG PET/CT whole body scan in the diagnosis of small bowel tumors. Methods The clinical data of 24 patients who had undergone 18F-FDG PET/CT whole body scan and were highly suspected with small bowel tumors were retrospectively analysed, and comparison analysis was conducted between results of PET/CT examinations and findings of double-balloon small bowel endoscopy, biopsy and surgical pathology. Results The data of 2 patients with extra-intestinal malignant tumors confirmed by pathology were excluded. Among the 22 patients with small bowel tumors, 16 patients were diagnosed as small bowel malignant tumors by 18F-FDG PET/CT whole body scan (17 small bowel malignant tumor lesions and 27 involved lymph nodes), 4 patients were diagnosed as small bowel benign tumors and benign lesions, 1 patient with intestinal tuberculosis had false positive PET/CT findings, and 1 patient with small intestinal signet ring cell carcinoma had false negative PET/CT findings. The sensitivity and specificity of 18F-FDG PET/CT in diagnosis of small bowel malignant tumors were 94.12% and 80.00% respectively, and the positive predictive value, negative predictive value and accuracy in diagnosis were 94.12%, 80.00% and 90.91% respectively. Conclusion 18F-FDG PET/CT whole body scan is a feasible, safe, noninvasive and promising diagnostic tool for detecting small bowel malignancies, differentiating benign and malignant tumors, staging and guiding clinical treatment.

Key words: small bowel tumors, positron emission tomography, computed tomography, X-ray computed, diagnosis