›› 2015, Vol. 35 ›› Issue (10): 1565-.doi: 10.3969/j.issn.1674-8115.2015.10.027

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Advances of γ-aminobutyric acid of patients with mental disorders by magnetic resonance spectroscopy technology

ZHANG Zong-feng, FAN Qing, WANG Yuan, ZHANG Hai-yin, WANG Zhen, XIAO Ze-ping   

  1. Shanghai Mental Health Center, Shanghai Clinical Center for Mental Disorders, Shanghai Jiao Tong University School of Medicine, Shanghai200030, China
  • Online:2015-10-20 Published:2015-12-22
  • Supported by:

    National Natural Science Foundation of China, 81171280, 81301153; National Key Clinical Disciplines at Shanghai Mental Health Center, OMA-MH 2011-873; The Key Characteristic Specialist Department of Shanghai Mental Health Center, 2013-YJTSZK-02


The abnormalities of functions of γ-aminobutyric acid neurons in the brain are found in a variety of mental disorders, such as anxiety disorder, mood disorder, sleep disorder, schizophrenia, autism spectrum disorder, and obsessive-compulsive disorder, etc. This paper reviews advances in studies on the effects of γ-aminobutyric acid on mental disorders by the magnetic resonance spectroscopy technology.

Key words: γ-aminobutyric acid, magnetic resonance spectroscopy technology, mental disorders