›› 2019, Vol. 39 ›› Issue (6): 655-.doi: 10.3969/j.issn.1674-8115.2019.06.015

• Review • Previous Articles     Next Articles

Modulating neural circuits in substance addiction with repetitive transcranial magnetic stimulation

XU Xiao-min, CHEN Tian-zhen, JIANG Hai-feng   

  1. Department of Drug Dependence, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2019-06-28 Published:2019-07-26
  • Supported by:
    National Natural Science Foundation of China, 81601164; Medical Guidance Program of Science and Technology Innovation Plan in Shanghai, 18411961200; Municipal Human Resources Development Program for Outstanding Young Talents in Medical and Health Sciences in Shanghai, 2017YQ013; Feixiang Program of Shanghai Mental Health Center, 2016-FX-003; Multicenter Clinical Trial Project of Shanghai Jiao Tong University School of Medicine, DLY201818)。

Abstract: Substance addiction is a chronic and recurrent disorder and may be related to complex neural circuits. However, there is no optimally effective treatment for substance addiction currently. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive, safe and easy-to-operate neuroelectrophysiological technique, which is becoming an emerging therapeutic option for many mental disorders. The effect of rTMS on substance addiction is closely related to the stimulation of neural circuits. However, the mechanism is still unknown. The review summarizes recent research progress on the application of rTMS and its application combined with other therapies in substance addiction, as well as the regulation of rTMS on substance addiction-related neural circuits.

Key words: substance addiction, repetitive transcranial magnetic stimulation (rTMS), brain neural circuit, therapy, craving

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