JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE) ›› 2021, Vol. 41 ›› Issue (1): 99-102.doi: 10.3969/j.issn.1674-8115.2021.01.018

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Research progress of sedative-hypnotics abuse and the interventions

Yu-jian YE(), Na ZHONG, Min ZHAO()   

  1. Department of Drug Dependence, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2021-01-28 Published:2021-02-22
  • Contact: Min ZHAO;
  • Supported by:
    Funding Information] National Natural Science Foundation of China(81771436);Shanghai Outstanding Academic Leaders Plan(17XD1403300);Shanghai Municipal Science and Technology Major Project(2018SHZDZX05);Significant Research Plan of Research Center of Shanghai Mental Health Center(CRC2018YB02)


For the fast-action, reliable efficacy and high safety, sedative-hypnotics have become the first-line drugs for insomnia, anxiety, epileptic seizure and alcohol-dependence withdrawal treatment. Rational use of such drugs has important application value in clinic. However, abuse or misuse might lead to adverse consequences such as memory impairment and increased risk of accidental injury. There have been some studies aiming at patients or prescribers to reduce the risk of overuse of sedative-hypnotics. This article reviews the prevalence of sedative-hypnotics abuse and corresponding interventions, with a view to providing the evidence of rational application as well as the basis for the subsequent researches on sedative-hypnotics.

Key words: sedative-hypnotics, drug abuse, intervention

CLC Number: