JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE) ›› 2021, Vol. 41 ›› Issue (2): 273-276.doi: 10.3969/j.issn.1674-8115.2021.02.024

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Evaluation of ocular surface following lip mucosa graft for palpebral margin defect

Xu-sheng WU(), Yue WU, Chun-yi SHAO(), Jin LI()   

  1. Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai 200011, China
  • Received:2020-06-17 Online:2021-02-28 Published:2021-02-28
  • Contact: Chun-yi SHAO,Jin LI E-mail:18817865201@163.com;wujunshabu@126.com;abcd1971206@126.com
  • Supported by:
    National Key R&D Program of China(2018YFC1106100);National Natural Science Foundation of China(81870688);Natural Science Foundation of Shanghai(19441900800);Shanghai Pujiang Program(18PJD025);Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support(20191914)

Abstract: Objective

·To analyze the condition of ocular surface and tear film after reconstruction of palpebral margin with lip mucosa graft.

Methods

·Fifteen patients with palpebral margin defect who were treated in the Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine from November 2017 to December 2019 were selected. All patients underwent the lip mucosa graft for palpebral margin reconstruction. A series of ocular surface examination, some ophthalmological physical examination and a questionnaire were prepared for each patient 6?8 weeks after surgery. The ocular surface examination was constituted of tear meniscus height (TMH), tear break-up time (BUT) and Schirmer test. The ophthalmological physical examination included affected palpebral fissure height (PFH) and levator function (LF). Finally, Ocular Surface Disease Index (OSDI) was used as a questionnaire.

Results

·There was no significant difference in TMH between fellow eyes and operated eyes [(0.24±0.07) mm vs (0.23±0.11) mm, P=0.316]. There was no significant difference in BUT between fellow eyes and operated eyes [(10.75±2.31) s vs (7.75±2.05) s, P=0.065]. There was no significant difference in the result of Schirmer text between fellow eyes and operated eyes [(10.20±1.96) mm/5 min vs (9.33±2.04) mm/5 min, P=0.376]. There was no significant difference in PFH between fellow eyes and operated eyes [(10.16±1.18) mm vs (10.11±2.11) mm, P=0.761]. There was no significant difference in LF between fellow eyes and operated eyes [(9.59±0.93) mm vs (9.03±1.02) mm, P=0.552]. The score of OSDI was 26.44±3.88 in average.

Conclusion

·The lip mucosa graft for treating palpebral margin defects gives a satisfactory result in tear film stability and binocular symmetry. Patients may have dry eyes according to the score of OSDI 6?8 weeks after surgery.

Key words: palpebral margin defect, lip mucosa graft, palpebral margin reconstruction, ocular surface

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