Evaluation of ocular surface following lip mucosa graft for palpebral margin defect

doi:10.3969/j.issn.1674-8115.2021.02.024

Abstract

Abstract: Objective

·To analyze the condition of ocular surface and tear film after reconstruction of palpebral margin with lip mucosa graft.

Methods

·Fifteen patients with palpebral margin defect who were treated in the Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine from November 2017 to December 2019 were selected. All patients underwent the lip mucosa graft for palpebral margin reconstruction. A series of ocular surface examination, some ophthalmological physical examination and a questionnaire were prepared for each patient 6?8 weeks after surgery. The ocular surface examination was constituted of tear meniscus height (TMH), tear break-up time (BUT) and Schirmer test. The ophthalmological physical examination included affected palpebral fissure height (PFH) and levator function (LF). Finally, Ocular Surface Disease Index (OSDI) was used as a questionnaire.

Results

·There was no significant difference in TMH between fellow eyes and operated eyes [(0.24±0.07) mm vs (0.23±0.11) mm, P=0.316]. There was no significant difference in BUT between fellow eyes and operated eyes [(10.75±2.31) s vs (7.75±2.05) s, P=0.065]. There was no significant difference in the result of Schirmer text between fellow eyes and operated eyes [(10.20±1.96) mm/5 min vs (9.33±2.04) mm/5 min, P=0.376]. There was no significant difference in PFH between fellow eyes and operated eyes [(10.16±1.18) mm vs (10.11±2.11) mm, P=0.761]. There was no significant difference in LF between fellow eyes and operated eyes [(9.59±0.93) mm vs (9.03±1.02) mm, P=0.552]. The score of OSDI was 26.44±3.88 in average.

Conclusion

·The lip mucosa graft for treating palpebral margin defects gives a satisfactory result in tear film stability and binocular symmetry. Patients may have dry eyes according to the score of OSDI 6?8 weeks after surgery.

Key words: palpebral margin defect, lip mucosa graft, palpebral margin reconstruction, ocular surface

CLC Number:

R777.1

Xu-sheng WU, Yue WU, Chun-yi SHAO, Jin LI. Evaluation of ocular surface following lip mucosa graft for palpebral margin defect[J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(2): 273-276.

Figures/Tables 3

TrendMD

References 26

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No	Gender	Age/year	Eye	Ratio of defect to palpebral fissure length	Cause of defect
1	Male	22	Right	2/3	Trauma
2	Male	51	Right	1/2	After eyelid tumor resection
3	Male	47	Left	1/2	After eyelid tumor resection
4	Female	41	Left	2/3	Trauma
5	Male	46	Left	1/2	After eyelid tumor resection
6	Female	39	Right	4/5	Chemical burn
7	Male	44	Left	2/3	Chemical burn
8	Female	37	Left	1/2	Chemical burn
9	Male	53	Right	4/5	Chemical burn
10	Female	72	Right	4/5	After eyelid tumor resection
11	Female	67	Left	1/2	After eyelid tumor resection
12	Female	46	Right	1/2	After eyelid tumor resection
13	Male	19	Left	2/3	Trauma
14	Male	51	Left	1/2	After eyelid tumor resection
15	Female	66	Left	1/2	Chemical burn

No	Gender	Age/year	Eye	Ratio of defect to palpebral fissure length	Cause of defect
1	Male	22	Right	2/3	Trauma
2	Male	51	Right	1/2	After eyelid tumor resection
3	Male	47	Left	1/2	After eyelid tumor resection
4	Female	41	Left	2/3	Trauma
5	Male	46	Left	1/2	After eyelid tumor resection
6	Female	39	Right	4/5	Chemical burn
7	Male	44	Left	2/3	Chemical burn
8	Female	37	Left	1/2	Chemical burn
9	Male	53	Right	4/5	Chemical burn
10	Female	72	Right	4/5	After eyelid tumor resection
11	Female	67	Left	1/2	After eyelid tumor resection
12	Female	46	Right	1/2	After eyelid tumor resection
13	Male	19	Left	2/3	Trauma
14	Male	51	Left	1/2	After eyelid tumor resection
15	Female	66	Left	1/2	Chemical burn

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