›› 2010, Vol. 30 ›› Issue (2): 229-.

• Review • Previous Articles     Next Articles

Research advance in role of ROS in cardioprotection offered by preconditioning or postconditioning

XIN Ping, reviewer；ZHU Wei, WEI Meng, reviser   

  1. Department of Cardiology, The Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 200233, China
  • Online:2010-02-25 Published:2010-02-25
  • Supported by:

    Shanghai Jiaotong University School of Medicine Foundation, BXJ0932

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Abstract:

Reactive oxygen species (ROS) play an important role in the cardiac ischemic and reperfusion injury. However, accumulating evidences have demonstrated that ROS are pivotal components of redox signaling cascade relevant to cardioprotection induced by either preconditioning or postconditioning. In this review, the definition, source and detection methods of ROS are introduced. Besides, the role of ROS in the cardioprotection offered by preconditioning or postconditioning and the effects of either preconditioning or postconditioning on ROS are summarized.

Key words: reactive oxygen species, myocardial reperfusion injury, preconditioning, postconditioning