Abstract:

Objective To explore the relationship between depth of burn wound and volume of fluid infusion during shock stage. Methods The clinical data of patients with total burn surface area no less than 25% of total body surface area and undergoing fluid infusion by Ruijin resuscitation formula during shock stage were collected. The total burn surface area, full-thickness burn surface area and volumes of fluid infusion in the first and second 24 h after burn were recorded, the ratio of full-thickness burn surface area to burn surface area (full-thickness burn surface area ratio) was calculated, and volumes infused per body weight and burn surface area （VIWB）in the first and second 24 h after burn were obtained. The relationship between full-thickness burn surface area ratio and VIWB was explored, the regression equations were established, and the corrected VIWB in the first and second 24 h after burn were calculated. Results The data of 166 patients were included. Compared with VIWB of patients with superficial burn （n=53）, those of patients with fullthickness burn （n=7） increased 37% and 41% in the first and second 24 h after burn, respectively (P<0.05). Fullthickness burn surface area ratio was significantly positively related to VIWB in the first and second 24 h after burn (R2=0.138, P<0.001; R2=0.108, P<0.001). The regression equations were y=0.537x+1.595 and y=0.314x+0.775. Compared with corrected VIWB in the first and second 24 h after burn of patients with superficial burn, those of patients with full-thickness burn and same burn surface area increased 35% and 41%, respectively. With each 20% increase in full-thickness burn surface area ratio, the corrected VIWB in the first and second 24 h after burn increased 0.1 and 0.06, respectively. Conclusion Full-thickness burn surface area ratio is related to volume of fluid infusion during shock stage, and corrected formula is suitable to VIWB of different depth of burn wound.

Key words: burn, shock, fluid therapy, depth of wound