›› 2011, Vol. 31 ›› Issue (2): 194-.doi: 10.3969/j.issn.1674-8115.2011.02.017

• Original article (Clinical research) • Previous Articles     Next Articles

Evaluation of left ventricular remodeling and function by quantitative real-time three-dimensional echocardiography in patients with acute myocardial infarction

ZHENG Li1,2, HUANG Guo-qian3, WANG Cheng1   

  1. 1.Department of Biomedical Engineering, Basic Medical College, Shanghai Jiaotong University, Shanghai 200025, China；2.Department of Ultrasound, The Third People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 201900, China；3.Department of Echocardiography, Huashan Hospital, Fudan University, Shanghai 200040, China
  • Online:2011-02-28 Published:2011-03-01
  • Supported by:

    Foundation from Shanghai Jiaotong University, YG2009MS02

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Abstract:

Objective To investigate the application of quantitive real-time three-dimensional echocardiography (RT-3DE) in evaluation of left ventricular remodeling and function in patients with acute myocardial infarction(AMI). Methods Thirtyfive patients with AMI (AMI group) were divided into 3 subgroups according to the results of coronary angiography. In subgroup A (n=9), left anterior descending artery was not involved; in subgroup B (n=9), only left anterior descending artery was involved; and in subgroup C (n=17), left anterior descending artery was involved in multi-vessel disease. Besides, 29 healthy subjects were served as normal controls. Left ventricular volume and left ventricular function were measured by two-dimensional echocardiography (2DE) biplane Simpson's method and RT-3DE. Results There was no significant difference between the findings of RT-3DE and those of Simpson's methods in normal control group （P>0.05）. In AMI group, LVEDV and LVESV measured by Simpson's method were lower than those measured by RT3DE, while EF measured by Simpson's method was higher than that measured by RT-3DE （P＜0.05）. There was no significant difference between the findings of RT-3DE and those of Simpson's methods in subgroup A and subgroup B （P>0.05）. In subgroup C, LVEDV and LVESV measured by Simpson's method were lower than those measured by RT-3DE, while EF measured by Simpson's method was higher than that measured by RT-3DE （P＜0.01）. LVEDV and LVESV in subgroup C were significantly higher than those in subgroup A and subgroup B measured by RT-3DE, while EF in subgroup C was significantly lower than that in subgroup A and subgroup B measured by RT-3DE (P＜0.01）. Conclusion RT-3DE allows non-invasive, accurate and quantitative evaluation of left ventricular remodeling and function in patients with AMI, and it is of clinical significance for those with severe and extensive coronary artery disease, such as multi-vessel coronary disease with left anterior descending artery involved.

Key words: real-time three-dimensional echocardiography, acute myocardial infarction, left ventricular remodeling