Abstract:

Objective To evaluate the therapeutic effect and safety of calcipotriol betamethasone ointment on the treatment of non-generalized vitiligo. Methods Calcipotriol betamethasone ointment was topically applied to the vitiliginous patches once daily in 51 patients with non-generalized vitiligo for 3 months, and the therapeutic effect and adverse effect were observed in each month. Results Of these 51 patients, 8 had complete repigmentation, 21 achieved excellent response, 10 experienced improvement, and the other 12 achieved almost no response. The excellent response rate was 56.86% (29/51, area of repigmentation≥50%), and the effective rate was 76.47% (39/51, area of repigmentation≥10%). Conclusion Calcipotriol betamethasone ointment is effective and safe in the treatment of vitiligo, with less adverse effect.

Key words: vitiligo, treatment, vitmin D3, calcipotriol betamethasone