›› 2020, Vol. 40 ›› Issue (4): 539-.doi: 10.3969/j.issn.1674-8115.2020.04.021

• Review • Previous Articles     Next Articles

Research progresses in transcutaneous vagus nerve stimulation

GU Nan-nan, LI Chun-bo   

  1. 1. Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China; 2. Institute of Psychology and Behavioral Science, Shanghai Jiao Tong University, Shanghai 200030, China; 3. Brain Science and Technology Research Center, Shanghai Jiao Tong University, Shanghai 200030, China; 4. Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Chinese Academy of Science, Shanghai 200030, China
  • Online:2020-04-28 Published:2020-05-22
  • Supported by:
    Key Program of Clinical Research Center in Shanghai Mental Health Center (CRC2017ZD01).

Abstract: The vagus nerve is involved in the regulation of human inflammation, mood and pain. Stimulation of the vagus nerve has assured therapeutic effects on intracepilepsy and refractory depression. On the surface of the human body, the ear is the only area in which vagal afferent fibers distribute. According to the "bottom-up" mechanism of the signal processing, the central nervous system can be modulatedstimulating the peripheral nerve. Therefore, stimulation of the vagus nerve can regulate the activities of brain stem, thalamus, cerebral cortex and other related areas to produce therapeutic effects. Transcutaneous vagus nerve stimulation is a safe, low-cost, non-invasive physical therapy modified vagus nerve stimulation. This review focuses on the regulation of organ functiontranscutaneous vagus nerve stimulation and its application to diseases treatment.

Key words: transcutaneous vagus nerve stimulation, physical therapy, functional regulation, clinical application