JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE) ›› 2022, Vol. 42 ›› Issue (2): 225-229.doi: 10.3969/j.issn.1674-8115.2022.02.014

• Review • Previous Articles    

Effects of food-borne titanium dioxide nanomaterials on digestive tract tissues and gastrointestinal microbiome: a review of recent studies

Hao WANG(), Ran WANG, Qian BA()   

  1. Shanghai Jiao Tong University School of Public Health, Shanghai 200025, China
  • Received:2021-10-09 Online:2022-01-24 Published:2022-01-24
  • Contact: Qian BA E-mail:shinku@sjtu.edu.cn;qba@shsmu.edu.cn
  • Supported by:
    National Natural Science Foundation of China(81973078)

Abstract:

With the improvement of quality of life and changes of dietary habits, people's requirements for food should not only include food and clothing, but also color, aroma, taste, shape and meaning, in which food additives play a very important role. Titanium dioxide (TiO2) is often widely used as a pigment additive in food and daily necessities, so people will inevitably contact and ingest TiO2 nanomaterials in daily life. Based on this, the article reviews the effect of TiO2 nanomaterials on digestive tract tissues and gastrointestinal microbiome, as well as its direct and indirect pro-inflammatory effects in the occurrence and development of gastrointestinal inflammation, further providing reference improving the safety of TiO2 nanomaterials in the food field.

Key words: nanomaterial, titanium dioxide (TiO2), digestive tract, gastrointestinal microbiome, inflammatory response

CLC Number: