·The clinical data of 110 934 pregnant women treated in the International Peace Maternal & Child Health Hospital, Shanghai Jiao Tong University School of Medicine from January 2014 to December 2020 were analyzed retrospectively. According to the treated time, pregnant women in the 2015?2017 year-period (n=48 984) and 2018?2020 year-period (n=45 262) were selected as the research objects to analyze the incidence of emergency peripartum hysterectomy. Besides, a total of 108 pregnant women with intractable postpartum hemorrhage were selected as the research objects. The patients were divided into the uterine-removed group (n=22) and the uterine-preserved group (n=86) according to whether they had hysterectomy. The clinical data of the two groups were compared and analyzed by univariate analysis and multivariate Logistic regression model, and the risk factors of emergency peripartum hysterectomy were explored.

·Compared with the 2015?2017 year-period, the incidence of emergency peripartum hysterectomy decreased in the 2018?2020 year-period (P=0.039). Meanwhile, compared with the uterine-preserved group, the pregnant women in the uterine-removed group were older, with more than 2 pregnancies, monocyesis, pregnancy complications (placenta previa, placenta implantation, scarred uterus, etc.), amniotic fluid embolism and greater postpartum hemorrhage (all P<0.05). Multivariate Logistic regression analysis showed that the patients' age and the volume of postpartum hemorrhage were independent risk factors for emergency peripartum hysterectomy caused by intractable postpartum hemorrhage (P<0.05).

·The older the patients with intractable postpartum hemorrhage, the greater volume of postpartum hemorrhage, which is easy to lead to emergency peripartum hysterectomy. Clinical monitoring and intervention should be carried out as soon as possible to reduce the patients' incidence of emergency peripartum hysterectomy.