Advances of effects of chronic low-grade inflammation on pathophysiology of polycystic ovary syndrome

doi:10.3969/j.issn.1674-8115.2013.12.024

Abstract

Abstract:

Inflammation is closely related to the occurrence and development of metabolic syndrome. Polycystic ovary syndrome (PCOS) is the most common endocrinology

metabolic disease in reproductive women. Recent studies showed that PCOS is related to the situation of chronic low-grade inflammation, which is highly

correlated to long-term complications of PCOS. However, the new evidences indicated that chronic persistent inflammation may take part in the early

development of pathophysiology of PCOS, such as interaction between chronic inflammation and hyperandrogenism and insulin resistence. With the early

detection and treatment of chronic low-grade inflammation of PCOS, it can be a new direction of pathogenesis and treatment of PCOS.

Key words: polycystic ovary syndrome, chronic low-grade inflammation, insulin resistance, hyperandrogenism, anti-inflammation therapy

LIN Zi-jun, TAO Tao, LIU Wei. Advances of effects of chronic low-grade inflammation on pathophysiology of polycystic ovary syndrome[J]. , doi: 10.3969/j.issn.1674-8115.2013.12.024.

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Advances of effects of chronic low-grade inflammation on pathophysiology of polycystic ovary syndrome

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