›› 2015, Vol. 35 ›› Issue (10): 1497-.doi: 10.3969/j.issn.1674-8115.2015.10.013

Previous Articles     Next Articles

Randomized control trial on improving effect of methadone maintenance treatment by enhancing motivation

WANG Jun1, JIANG Hai-feng2, DU Jiang2, DONG Ai-zhen1, WANG Jian-guo1, FA Jin-mao1, ZHANG Huai-hui1, WU Yi1, AN Xiao-qun1, ZHAO Min2, SUN Hai-ming2   

  1. 1.Shanghai Yangpu District Mental Health Center, Shanghai200090, China; 2.Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai200030, China
  • Online:2015-10-20 Published:2015-12-22
  • Supported by:

    Advanced Appropriate Technology Promotion Project of Shanghai Health System, 2013SY011, 2014ZYJB0002; National Natural Science Foundation of China, 81271468


ObjectiveTo explore the effect of enhancing motivation (EM) of methadone maintenance treatment (MMT) clinic in Yangpu district of Shanghai.MethodsA total of 60 heroin dependents who recently underwent MMT were randomly divided into the control group (n=30) and intervention group (n=30). Patients of the intervention group underwent MMT and 12 weeks of EM and patients of the control group only underwent MMT. Results of MMT, morphine test, and addiction Severity Index (ASI) of two groups were compared.ResultsThe differences of average medication days (66 d versus 54 d) and number of negative urine tests (8.1 versus 6.2) between two groups were not statistically significant after 12 weeks of EM (P>0.05). But the professional and social supports, severity of drug use, alcohol addiction, and family/society relation of the intervention group were remarkably better than those of the control group during the 24 weeks of observation.ConclusionThe EM conducted in Yangpu district of Shanghai does not significantly improve the effect of MMT, but is helpful for improving the physical health and professional and social supports of heroin dependents, and decreasing the severity of drug use.

Key words: enhancing motivation, methadone maintenance treatment, heroin dependent