›› 2018, Vol. 38 ›› Issue (11): 1386-.doi: 10.3969/j.issn.1674-8115.2018.11.021

• Review • Previous Articles     Next Articles

Antibacterial mechanism and application of gold nanoparticles

CHU Guang-yu, CHEN Yun-feng   

  1. Department of Orthopedic Surgery, Shanghai Sixth Peoples Hospital, Shanghai Jiao Tong University, Shanghai 200233, China
  • Online:2018-11-28 Published:2018-12-15
  • Supported by:
    National Natural Science Foundation of China, 8167090574

Abstract: Multi-drug resistance is a major clinical challenge today. The good antibacterial effect of gold nanoparticles (AuNPs) based on their unique physical and chemical properties make such systems ideal for application as antibacterial drug carriers or self-modified therapeutic agents both in vitro and in vivo. AuNPs also have good clinical application prospects for their broad antibacterial spectrum, various antibacterial mechanisms and good biocompatibility. However, their structural stability in vivo, antibacterial mechanism, long-term safety and cytotoxicity of the surface modification have yet to be further explored and improved through subsequent studies.

Key words: gold nanoparticles, antibacterial, mechanism, biocompatibility

CLC Number: