JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE) ›› 2020, Vol. 40 ›› Issue (9): 1256-1262.doi: 10.3969/j.issn.1674-8115.2020.09.015

• Original article (Clinical research) • Previous Articles     Next Articles

Clinical characteristics and risk factors of male patients with alcohol-induced psychotic disorders

MA Yin-zhu*, LU Guang-hua*, ZHONG Na, WANG Hai-hong, HE Shen, ZHAO Xue, JIANG Hai-feng , WANG Zhen   

  1. Addiction Department, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 201100, China
  • Online:2020-09-28 Published:2020-11-04
  • Supported by:
    Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support (20161321); Hospital-level Project of Shanghai Mental Health Center (2019-YJ11, 2020-YJ14); Scientific Research Project of Shanghai Municipal Health Commission (20204Y0364).

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Abstract: Objective · To explore the clinical characteristics and risk factors of male patients with psychotic disorders caused by alcohol. Methods · The clinical data of 52 male inpatients with alcohol use and related disorders treated in the Department of Addiction of Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine from May 2018 to December 2019 were collected. There were 19 cases of alcohol-induced psychotic disorder (alcohol-induced psychosis disorder, AIPD) group and 33 cases of non-AIPD group. The risk factors of AIPD were obtained by regression analysis. Results · AIPD patients had a higher incidence of hallucinations (47.4%) and delusions of murder (47.4%). Compared with non-AIPD groups, Logistic regression analysis of AIPD patients showed that vitamine B12 (VB12) serum level (P=0.011, OR=0.995) and total cholesterol serum level (P=0.039, OR=1.874) were associated with the occurrence of AIPD. Conclusion · Patients with AIPD have psychiatric symptoms mainly consisting of hallucinations and delusions of murder. When patients’ laboratory tests show abnormal serum VB12 and serum total cholesterol levels, attentions should be paid to the occurrence of AIPD.

Key words: alcohol, psychotic disorder, vitamine B12 (VB12), clinical feature, risk factor

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