JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE) ›› 2020, Vol. 40 ›› Issue (12): 1660-1664.doi: 10.3969/j.issn.1674-8115.2020.12.017

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Advances in magnetic resonance imaging study of bipolar Ⅰdisorder

YANG Tao, CHEN Jun, FANG Yi-ru   

  1. Clinical Research Center, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2020-12-28 Published:2021-02-02
  • Supported by:
    National Key R&D Program of China (2016YFC1307100); National Natural Science Foundation of China (91232719, 81761128032); Sanming Project of Medicine in Shenzhen (SZSM201612006).

Abstract: The brain structural and functional impairment in affective and cognitive circuits has been detected in bipolar disorder (BD) patients; however the specific neuroimaging mechanism of BD is still inconsistent. One of the reasons may be the sample heterogeneity caused by subtypes of BD. Bipolar Ⅰdisorder (BD- Ⅰ ) is one of the BD types with the highest prevalence and the most typical symptoms. It may be better to reveal the mechanism of BD and explore targeted treatment through research focusing on BD- Ⅰ patients. This article reviews the magnetic resonance imaging (MRI) studies about BD- Ⅰ in recent 5 years to better know about advances in this field and explore the potential research directions.

Key words: bipolar Ⅰdisorder (BD- Ⅰ), magnetic resonance imaging (MRI), structure, function

CLC Number: