JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE) ›› 2021, Vol. 41 ›› Issue (7): 959-962.doi: 10.3969/j.issn.1674-8115.2021.07.018

• Review • Previous Articles    

Application of hydrogel sustained-release system to periodontal tissue regeneration

Tung-liang HSIA(), Jia-chen DONG, Rong SHU()   

  1. Department of Periodontology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology; National Clinical Research Center for Oral Diseases, Shanghai 200011, China
  • Online:2021-07-28 Published:2021-08-03
  • Contact: Rong SHU;
  • Supported by:
    National Natural Science Foundation of China(81570977);Natural Science Foundation of Shanghai(18ZR1422400);Cross-disciplinary Research Fund of Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine(JYJC201904)


As an emerging functional polymer material, hydrogel has great potential for development, and is widely used in bioengineering. Because of its good biocompatibility, it has also gradually received attention in the medical field. Some studies have shown that hydrogel sustained-release system can promote the proliferation and adhesion of human periodontal ligament fibroblasts and effectively promote their differentiation into osteoblasts and cementoblasts. This paper briefly reviews the application of hydrogel to periodontal tissue regeneration.

Key words: hydrogel, regeneration of periodontal tissue, tissue engineering, scaffold material

CLC Number: