Abstract:

Tissue engineering provides urologists a new way to fix or reconstruct the impaired organs. Reconstitution of corporal bodies of penis with engineered tissue substitutes has been applied in animal models. In hypospadias reconstruction, the use of engineered tissue substitutes has been applied clinically. The clinical application of bladder tissue substitutes has been ongoing phase II clinical trial. Great progress has been made in renal replacement therapy with clinical application of human progenitor cells in hemofiltration units, and the engineered intracorporeal renal replacement unit will come true by additional studies. The current status of tissue engineering in clinical practice of urology is reviewed in this paper.

Key words: tissue engineering, urology, clinical practice