Abstract:

Objective To investigate the outcomes of female primary bladder neck obstruction (PBNO) treated with transurethral resection of bladder neck (TURBN), and perform the pathological analysis. Methods Twenty-two women with PBNO were recruited, and preoperative examinations were conducted, including physical examination, urine routine, American Urological Association scoring, urodymamics, ultrasonography and cystoscopy. Bladder outlet obstruction was diagnosed according to Blaivas-Groutz nomogram, TURBN was performed with Olympus standard resectoscope, and urinary catheter was retained for 24 to 72 h after operation. Results There were 4 patients with severe obstruction, 10 patients with moderate obstruction and 8 patients with mild obstruction. Elevated posterior lip of bladder neck and trabecula hyperplasia of bladder wall were observed through cystoscopy. Twelve months after operation, all the symptoms and parameters were improved. Pathological examinations revealed glandular cystitis, fibrous tissue hyperplasia and chronic inflammation. Conclusion TURBN is an effective and safe method in treatment of PBNO, especially for patients with unsuccessful pharmacotherapy.

Key words: primary bladder neck obstruction, transurethral resection of bladder neck, female