上海交通大学学报（医学版）

上海交通大学学报（医学版）

• 论著（临床研究） • 上一篇    下一篇

超声引导下细针穿刺活检对甲状腺小结节的诊断价值

郑 瑜，石有振，李蒙森，朱美琴，郑 丽   

  1. 上海交通大学 医学院附属第三人民医院超声诊断科， 上海 201999
  • 出版日期:2014-08-28 发布日期:2014-09-02
  • 通讯作者: 郑 丽, 电子信箱: zli9798@163.com。
  • 作者简介:郑 瑜（1971—）， 女， 主治医师， 学士; 电子信箱: 12139423@qq.com。
  • 基金资助:

    上海交通大学医学院校级(自然)基金（12XJ10030）；上海市宝山区科技发展基金（12-E-1）

Value of ultrasound-guided fine-needle aspiration biopsy for diagnosis of small thyroid nodules

ZHENG Yu, SHI You-zhen, LI Meng-sen, ZHU Mei-qin, ZHENG Li   

  1. Department of Ultrasound, the Third People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201999, China
  • Online:2014-08-28 Published:2014-09-02
  • Supported by:

    Natural Science Foundation of Shanghai Jiao Tong University School of Medicine,12XJ10030; Science and Technology Development Foundation of Baoshan District of Shanghai,12-E-1

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摘要：

目的 探讨超声引导下细针穿刺活检（US-FNAB）对＜10 mm甲状腺小结节的诊断价值。方法 回顾性分析105例（共计115个）最大径＜10 mm甲状腺结节患者的临床资料，评估US-FNAB细胞学结果与手术病理及临床随访结果对照。结果 115个甲状腺小结节中，细胞学诊断恶性24例，可疑恶性9例，良性68例，不确定4例，不满意10例。经术后病理或临床随访，恶性结节26个，良性结节89个。US-FNAB诊断＜10 mm甲状腺小结节的灵敏度为88.9%(24/27)，特异度为90.0%(79/88)，准确率为90.0%(103/115)。结论 US-FNAB对＜10 mm甲状腺结节诊断的准确性好，具有较高的临床实用价值。

关键词: 甲状腺小结节, 超声引导, 细针穿刺活检

Abstract:

Objective To investigate the value of ultrasound-guided fine-needle aspiration biopsy (US-FNAB) for the diagnosis of thyroid nodules smaller than 10 mm in diameter. Methods The clinical data of 105 patients (115 thyroid nodules) with thyroid nodules smaller than 10 mm were retrospectively analyzed. The cytologic results of US-FNAB were evaluated and compared to the surgical pathological results and clinical follow-up results. Results Among 115 small thyroid nodules diagnosed by the cytology, 24 nodules were malignant; 9 nodules were suspicious for malignancy; 68 nodules were benign; 4 nodules were uncertain; and 10 nodules were inadequate. Actually there were 26 malignant nodules and 89 benign nodules confirmed by clinical follow-ups and pathological results. The sensitivity, specificity, and accuracy of US-FNAB for the diagnosis of thyroid nodules smaller than 10 mm were 88.9% (24/27), 90.0% (79/88), and 90.0% (103/115), respectively. Conclusion US-FNAB is accurate for the diagnosis of thyroid nodules smaller than 10 mm and valuable for practical application.

Key words: small thyroid nodules, ultrasound-guided, fine-needle aspiration biopsy