上海交通大学学报（医学版）

上海交通大学学报（医学版） ›› 2018, Vol. 38 ›› Issue (5): 565-.doi: 10.3969/j.issn.1674-8115.2018.05.017

• 综述 • 上一篇    下一篇

湿化高流量鼻导管通气治疗儿科患者的临床研究进展

童兴瑜，尤纱纱，曹慧敏，何斌   

  1. 上海交通大学医学院附属新华医院麻醉与重症医学科，上海 200092
  • 出版日期:2018-05-28 发布日期:2018-05-28
  • 通讯作者: 何斌，电子信箱：hebin@xinhuamed.com.cn。
  • 作者简介:童兴瑜（1993—），女，硕士生；电子信箱： 2433928723@qq.com。
  • 基金资助:
    国家自然科学基金（81470390）；上海市教育委员会高峰高原学科建设计划（20152218）；上海申康临床三年行动计划项目（16CR3006A）；上海市科学技术委员会科研计划项目（17411954700）

Clinical research progress of humidified high-flow nasal cannula therapy in pediatric patients

TONG Xing-yu, YOU Sha-sha, CAO Hui-min, HE Bin   

  1. Department of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
  • Online:2018-05-28 Published:2018-05-28
  • Supported by:
    National Natural Science Foundation of China, 81470390; Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Support, 20152218; Clinical Research Plan of Shanghai Hospital Development Center, 16CR3006A; Program of Science and Technology Commission of Shanghai Municipality, 17411954700

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摘要： 多种形式的无创呼吸支持可适用于婴儿呼吸窘迫和低氧血症的治疗。在新生儿重症监护病房最常见的是经鼻持续气道正压通气（nasal continuous positive airway pressure, NCPAP），但新生儿不易耐受，有继发黏膜损伤和院内感染的风险。近些年来，湿化高流量鼻导管通气（humidified high-flow nasal cannula, HHFNC）治疗已经被引入，因其增加了患儿的舒适度和耐受性同时保证通气的有效性，正逐渐成为替代 NCPAP的另一种无创呼吸支持模式。该文将对近些年 HHFNC治疗儿科患者的研究进展进行综述。

关键词: 经鼻持续气道正压通气, 湿化高流量鼻导管通气, 新生儿重症监护病房, 儿科患者

Abstract:

Various forms of noninvasive respiratory support have been applied to the treatment of infant respiratory distress and hypoxemia. The most common noninvasive respiratory support in neonatal intensive care unit is nasal continuous positive airway pressure (NCPAP). But the NCPAP systems are not always well acceptedthe neonatal population, with the risk of mucosal injury and nosocomial infection. In recent years, humidified high-flow nasal cannula (HHFNC) has been introduced and developed as a possible alternative to NCPAP for noninvasive respiratory support mode, becait increases patients’ comfort and the effectiveness of the ventilation. This article summarized the current research progress of HHFNC therapy in pediatric patients.

Key words: nasal continuous positive airway pressure, humidified high-flow nasal cannula, neonatal intensive care unit, pediatric patient

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