上海交通大学学报（医学版）

上海交通大学学报（医学版）

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白藜芦醇对肠道保护作用的研究进展

高润颖，蔡美琴   

  1. 上海交通大学 公共卫生学院， 上海 200025
  • 出版日期:2016-02-28 发布日期:2016-03-29
  • 通讯作者: 蔡美琴, 电子信箱: caimeiqin@sjtu.edu.cn。
  • 作者简介:高润颖（1991—）， 女， 硕士生; 电子信箱: dly-slyj@hotmail.com。

Research advances in protective effect of resveratrol on intestine

GAO Run-ying, CAI Mei-qin   

  1. Shanghai Jiao Tong University School of Public Health, Shanghai 200025, China
  • Online:2016-02-28 Published:2016-03-29

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摘要：

肠道具有消化吸收的生理功能和阻挡外源性有害物质入体的屏障功能，在维护机体机能方面发挥着极其重要的作用。白藜芦醇作为一种生物活性物质，通过抗炎、抗纤维化、抗氧化和抑制细胞凋亡等途径能缓解肠道功能障碍，保护受损肠道。该文综述了白藜芦醇对肠道保护作用的研究进展，为其作为膳食补充以及肠道疾病用药的可能性提供科学依据。

关键词: 白藜芦醇, 肠道, 抗炎, 抗纤维化, 抗氧化

Abstract:

Intestine has the physiological function of digestion and absorption, as well as barrier function of blocking exogenous harmful substances from human body. It also plays a very important role in maintaining body functions. As a physiological active substance, resveratrol can alleviate bowel dysfunction and protect impaired intestine through anti-inflammation, anti-fibrosis, anti-oxidation, and inhibition of apoptosis, etc. In this article, the research advances in the protective effect of resveratrol on intestinal function are reviewed, which can provide the scientific basis for the possible use of resveratrol as a dietary supplement or a medicine for intestinal diseases.

Key words: resveratrol, intestine, anti-inflammation, anti-fibrosis, anti-oxidation