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载脂蛋白A-Ⅰ与多囊卵巢综合征关系的研究进展

  • 仝腊娟 ,
  • 丘 彦
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  • 重庆医科大学附属第一医院辅助生育中心, 重庆 400016
仝腊娟(1986—), 女, 硕士生; 电子信箱: tonglajuan@yahoo.cn。

网络出版日期: 2013-12-03

Research advances in Apolipoprotein A-Ⅰ and polycystic ovary syndrome

  • TONG La-juan ,
  • QIU Yan
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  • Department of Assistant Reproductive Centre, the First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China

Online published: 2013-12-03

摘要

载脂蛋白A-Ⅰ(ApoA-Ⅰ)是参与胆固醇逆向转运(RCT)的重要因子,研究发现多囊卵巢综合征(PCOS)患者的ApoA-Ⅰ表达显著降低。ApoA-Ⅰ表达减少引起的胆固醇转运障碍,可能与PCOS患者的脂代谢异常和胰岛素抵抗等有关。

本文引用格式

仝腊娟 , 丘 彦 . 载脂蛋白A-Ⅰ与多囊卵巢综合征关系的研究进展[J]. 上海交通大学学报(医学版), 2013 , 33(11) : 1545 . DOI: 10.3969/j.issn.1674-8115.2013.11.024

Abstract

Apolipoprotein A-Ⅰ(ApoA-Ⅰ)is an important factor participating in the process of reverse cholesterol transport (RCT). In patients with polycystic ovary syndrome (PCOS), level of ApoA-Ⅰ was significantly low. The decreased expression of ApoA-Ⅰ could cause disorder of RCT, which may be connected with abnormal lipid metabolism and insulin resistance (IR) of PCOS patients.

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