›› 2012, Vol. 32 ›› Issue (9): 1128-.doi: 10.3969/j.issn.1674-8115.2012.09.003

• Editorial • Previous Articles     Next Articles

Autoimmune diseases: immuno-pathogenic dissection and strategy exploration for immune intervention

SHEN Hao1, WANG Ying1, WANG Jia-qi1, LI Ning-li1, WANG Hong-lin1, SHEN Nan2   

  1. 1.Shanghai Institute of Immunology, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China；2.Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200001, China
  • Online:2012-09-28 Published:2012-09-29

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Abstract:

Autoimmune diseases arise from inappropriate immune responses against molecules and organs normally present in the body, resulting in tissue damage and functional defects. Supported by “211 Project”, the research groups from Shanghai Institute of Immunology and Shanghai Institute of Rheumatology have been working cooperatively to explore the immuno-regulation and immuno-pathogenesis of important autoimmune disorders including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and psoriasis (PS), in which facilitate the diagnosis and intervention of the diseases. One of the research achievements, the pathogenesis of SLE and its novel therapeutic strategy, was awarded the second prize of 2009 National Science and Technology Progress Award.

Key words: systemic lupus erythematosus, rheumatoid arthritis, psoriasis, immune mechanism, immune intervention