›› 2010, Vol. 30 ›› Issue (12): 1540-.doi: 10.3969/j.issn.1674-8115.2010.12.022

• Original article (Clinical research) • Previous Articles     Next Articles

Application of low-dose dual-source CT in diagnosis of coronary lesions in patients with Kawasaki disease

JIN Biao   

  1. Department of Radiology, Xinhua Hospital (Chongming Branch), Shanghai Jiaotong University School of Medicine, Shanghai 202150, China
  • Online:2010-12-25 Published:2010-12-31


Objective To investigate the value of low-dose dual-source CT in the diagnosis of coronary lesions in patients with Kawasaki disease. Methods Thirty-eight children (29 boys and 9 girls) diagnosed as Kawasaki disease underwent coronary CT angiography using dual-source CT. ECG-gated coronary acquisition were applied in 8 patients who could hold breath, and non-ECG-gated conventional thoracic spiral CT were used in 30 patients who could not hold breath. A setting of 80 kV in voltage was implemented. The number, location and size of coronary aneurysms were recorded, and were compared with echocardiographic findings. The radiation doses of patients were calculated. Results A total of 47 coronary aneurysms were demonstrated, with mean diameter of (8.4±3.5) mm and mean length of (13.8±7.4) mm. Ten aneurysms were small, 15 were medium and the other 22 were giant in size. Among the aneurysms in left coronary artery, 8, 13, 5 and 6 were located in the main branch, proximal segment, middle segment and circumflex branch, respectively. Among the aneurysms in right coronary artery, 8, 6 and 1 were located in the proximal, middle and distal segment, respectively. Ten stenotic segments were demonstrated, with calcification in 8 aneurysms. The mean radiation dose was (0.46±0.24)mSv. Echocardiography failed to detect 5 small aneurysms located in the middle and distal segment of coronary arteries. Conclusion Dual-source CT is an useful tool in the diagnosis of coronary lesions in patients with Kawasaki disease, and is a supplement to echocardiography.

Key words: dual-source CT, radiation dosage, coronary vessels, Kawasaki disease