Abstract:

Serum thyroid stimulating hormone (TSH) is a most sensitive parameter for thyroid function. There are various techniques for detection of serum TSH, which has evolved from radioimmunoassay and immunoradiometric assay to immunochemiluminometric assay, electro chemiluminescence immunoassay, time-resolved fluoroimmunoassay immunochemiluminometry and microfluidic chip technique, with the detection sensitivity significantly improved. The clinically commonly used techniques for detection of serum TSH are introduced in this paper.

Key words: serum thyrotropin, labeled immunoassay, interference, clinical application