Abstract:

Nanoparticles provide a new approach for antitumor drug delivery as a carrier for penetrating tumor vasculature and entering into tumor cells. After modification for nanoparticles, these particles target to tumor cell membranes, tumor microenvironment, cytoplasmic or nuclear receptors. Nanoparticles deliver high concentration of drug to the targeted tumor cells, with reduced toxicity to normal tissues. In this article, the mechanisms and latest researches on the application of nanoparticles in the treatment of breast cancer are reviewed.

Key words: nanoparticles, breast cancer, drug delivery