›› 2010, Vol. 30 ›› Issue (7): 852-.

• Review • Previous Articles     Next Articles

Roles of small intestinal bacterial overgrowth in pathogenesis of irritable bowel syndrome

SHEN Feng1, reviewer；CHEN Guang-yu2, LI Ding-guo2, reviser   

  1. 1.Department of Gastroenterology, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200092, China；2.Clinical Epidemiological Unit, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China
  • Online:2010-07-25 Published:2010-07-26

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Abstract:

Small intestinal bacterial overgrowth (SIBO) refers to a condition in which abnormally large numbers of anaerobic bacteria present in the small intestine, and patients with SIBO typically complain of diarrhea, bloating and some symptoms induced by malabsorption and dysfunction of intestinal transit. The symptoms of SIBO are similar to those of irritable bowel syndrome (IBS). Relevant studies have revealed that SIBO is related to IBS, and it has been hypothesized that SIBO may be an underlying cause for IBS. The research progress of roles of SIBO in the pathogenesis of IBS is reviewed in this paper.

Key words: small intestinal bacterial overgrowth, irritable bowel syndrome, pathogenesis