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Progress toward cell wall glycoconjugates of Mycobacterium tuberculosis

ZOU Yun1, LIN Wen-feng1, ZHANG Shu-lin2   

  1. 1.Grade 2009 of Eight-year Clinical Medicine Major, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China; 2.Department of Pathogenic Biology, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Online:2013-11-28 Published:2013-12-03
  • Supported by:

    Foundation of Shanghai Commission of Science and Technology, China, 12441903300

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Abstract:

Tuberculosis (TB), a chronic infectious disease mainly associated with respiratory tract, caused by Mycobacterium tuberculosis, is still the highest mortality infectious diseases of simplex cause today. Therefore a further understanding of physiological metabolism and pathogenesis of TB is critical to the control and prevention of TB spread. The special glycoconjugates in Mycobacterium tuberculosis's cell wall play an important role in the maintenance of cell wall integrity and its pathological process, thus becoming a focus of relevant researches. To provide a basis for basic research and clinical application of TB, the recent advance in major cell wall glycoconjugates of Mycobacterium tuberculosis is summarized in this paper.

Key words: Mycobacterium tuberculosis, cell wall, glycoconjugates