Advances of radionuclide imaging for cell apoptosis

doi:10.3969/j.issn.1674-8115.2015.11.029

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Advances of radionuclide imaging for cell apoptosis

LIU Qiu-fang, SONG Shao-li

Department of Nuclear Medicine， Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China

Online:2015-11-28 Published:2016-01-13
Supported by:
National Natural Science Foundation of China, 81101073, 81471708; Biomedical Engineering Cross Research Foundation of Shanghai Jiao Tong University, YG2012MS13

Abstract

Abstract:

Radionuclide imaging for the cell apoptosis is a direct, noninvasive, and real-time imaging technique. It is a hopeful method for observing brain and myocardial ischemic reperfusion injury, detecting allograft rejection, and evaluating the effects of tumor chemotherapy and radiotherapy. This paper introduces the design, mechanisms, and applications of radionuclide agents based on preclinical studies.

Key words: apoptosis, radionuclide agent, phosphatidylserine, Annexin, synaptotagmin Ⅰ, caspase

LIU Qiu-fang, SONG Shao-li. Advances of radionuclide imaging for cell apoptosis[J]. , doi: 10.3969/j.issn.1674-8115.2015.11.029.

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Advances of radionuclide imaging for cell apoptosis

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