Abstract:

Single umbilical artery (SUA) is relevant to the increasing incidence of various congenital malformations, especially the congenital heart disease, and has been regarded as an indication for referring to fetal echocardiography. However, whether isolated single umbilical artery (iSUA) without extracardiac abnormalities should be referred to fetal echocardiography is still controversial. This paper reviewed the correlation between SUA and congenital malformation, summarized recent perspectives about whether iSUA should be referred to fetal echocardiography, analyzed current status and research advances of referral of fetal echocardiography at home and abroad, and provided a reference for whether isolated iSUA should be an indication for referring to fetal echocardiography.

Key words: isolated single umbilical artery, congenital heart disease, fetal echocardiography, referral