Abstract: Objective · To investigate and compare the curative effect of rubber ring and dental floss combined with hemoclipping assisted endoscopic submucosal dissection(ESD) on gastrointestinal tumors.  Methods · A total of 54 patients with gastrointestinal tumors were collected. Twenty-seven patients in rubber ring group accepted ESD assisted by rubber ring with hemoclipping, and the other 27 patients in dental floss group accepted ESD assisted by dental floss with hemoclipping. Duration of the operation, installation time of the traction device, detachment frequency of hemoclipping, injury of mucosa, one-time complete resection rate, and complication rate were analyzed as key indicators.  Results · The detachment frequency of hemoclipping in rubber ring group was significantly less than that in dental floss group (t=4.418, P<0.05). There was no injury of mucosa in rubber ring group, while, three patients had mucosa injury in dental floss group. There was no statistically significant difference on duration of operation, installation time of traction device, one-time complete resection rate, and complication rate between two groups. After 2 ～ 12 months of follow-up, the wound healed well in all patients in rubber ring group. No evidence of tumor recurrence was noted.  Conclusion · Compared with dental floss, rubber ring combined with hemoclipping is superior in assisted ESD, especially in the right half colon. It is an effective assist device with little trauma and adjustable direction.

Key words: rubber ring, hemoclipping, dental floss, traction, endoscopic submucosal dissection, gastrointestinal tumour