MicroRNA: a novel regulatory molecule of acute lung injury

doi:10.3969/j.issn.1674-8115.2014.10.025

• Review • Previous Articles Next Articles

MicroRNA: a novel regulatory molecule of acute lung injury

CAO Yong-mei, LI Ying-chuan

Department of Anesthesiology, the Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China

Online:2014-10-28 Published:2014-10-28
Supported by:
National Natural Science Foundation of China，81272145； Foundation of Shanghai Municipal Health Bureau，2009089

Abstract

Abstract:

Acute lung injury (ALI) is a common and complex disease characterized by severe pulmonary inflammation. As a new type of gene regulator, microRNA (miRNA) plays vital roles in a wide range of human disorders and diseases, including ALI. During the process of lung injury and repair, certain kinds of miRNA express abnormally and can modulate inflammation pathways as well as immune response by affecting expressions of target genes. Therefore, miRNA can serve as biological markers for ALI. This paper reviews the effects of miRNA on ALI.

Key words: microRNA, acute lung injury, inflammation, immune response

CAO Yong-mei, LI Ying-chuan. MicroRNA: a novel regulatory molecule of acute lung injury[J]. , doi: 10.3969/j.issn.1674-8115.2014.10.025.

[1]	Shu-jun WAN, Xiang KONG, Kun LÜ. Relationship between non-coding RNAs and vascular diseases of diabetes mellitus [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(5): 665-670.
[2]	Jing-yi FU, Lei WANG, Yi YANG. Research progress in animal model of acute lung injury [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(5): 690-694.
[3]	Ze-nan WU, Chen ZHANG. Research advances in inflammatory mechanism of anhedonia [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(2): 241-245.
[4]	Liang-jun LIN, Wei-di WANG, Pei WANG, Guan-ning LIN, Zhen WANG. Research progress in epigenetics of obsessive-compulsive disorder [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2021, 41(2): 267-272.
[5]	HU Yi1, 2, ZHOU Wei2, SONG Zhong-chen1, 2. Peripheral and central inflammatory changes in experimental periodontitis rats [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2020, 40(12): 1579-1584.
[6]	CAO Li-yuan, MU Wei. Inducers and inhibitors of necroptosis and their research progress in diseases [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2020, 40(11): 1524-1529.
[7]	YUAN Qing-yue, ZHUANG Ai, SONG Xue-fei, SHI Wo-dong, BI Xiao-ping. Effect of sinus inflammation on the prognosis of blowout orbital fracture [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2020, 40(10): 1398-1401.
[8]	WANG Qi, ZHU Guan-ya, XIE Ting, GE Kui, NIU Yi-wen. Changes of ATP metabolism and purinergic receptors in inflammatory response stage of diabetic wound healing [J]. , 2020, 40(1): 10-.
[9]	HE Hai-ning, ZHANG Wei, YAN Feng, SHI Yan-chen, WANG Jing-hua, XIAO Shi-fu#, WANG Tao#. Bioinformatics analysis of miRNAs in mild cognitive impairment due to Alzheimer's disease [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2020, 40(09): 1174-1183.
[10]	LI Sen1, JIA Zi-heng1, WEI Xue-rui1, MA Sai1, LU Tian-cheng1, LI Ting-ting2, GU Yan-yun2. Role of bile acid on maintaining metabolic homeostasis [J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2020, 40(08): 1126-1130.
[11]	CHU Wei-wei, XU Jie-ying, LI Shang, ZHAI Jun-yu, DU Yan-zhi. Gut microbiota of polycystic ovary syndrome model rats induced with dehydroepiandrosterone [J]. , 2019, 39(9): 975-.
[12]	LU Hai-yang, ZHAO Wei-li. Role of gastrointestinal microbiota in tumorigenesis [J]. , 2019, 39(9): 1083-.
[13]	LONG Quan1, QIN Ji-ping2, LI Rong2, CHANG Juan2, JIANG Geng-ru3, ZHU Chun2, 3. Effects of hemodialysis and hemoperfusion combination treatment on maintenance hemodialysis patients [J]. , 2019, 39(8): 886-.
[14]	XIE Xiao-hua1, CHEN Ze1, LIU Cheng-bo1, YANG Yi-hui2, ZHANG Yong-jun1. Improvement of batyl alcohol on alveolarization arrest in newborn rats with bronchopulmonary dysplasia [J]. , 2019, 39(7): 714-.
[15]	WANG Hao1, JIANG Shan1, GONG Yang-ming2, LIU Yan3, HUA Li1, DENG Xiao-bei1. Atmospheric fine particulate matter causing Alzheimers disease through olfactory bulb pathway: a review of recent studies [J]. , 2019, 39(6): 666-.

MicroRNA: a novel regulatory molecule of acute lung injury

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

TrendMD

References

Related Articles 15

Recommended Articles

Metrics

Comments