JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE) ›› 2021, Vol. 41 ›› Issue (1): 123-125.doi: 10.3969/j.issn.1674-8115.2021.01.023

• Case report • Previous Articles     Next Articles

A case report of fundus hemorrhage in recurrent acute myeloid leukemia

Ting QIU(), Jing JIN, Yuan-yue CUI, Lei SONG, Xie LI, Ji-fang QU()   

  1. Department of Ophthalmology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
  • Online:2021-01-28 Published:2021-02-22
  • Contact: Ji-fang QU;
  • Supported by:
    Funding Information] Project of Shanghai Science and Technology Commission(19401932200);Project of Shanghai Municipal Health Commission(20194Y0268)


A 16-year-old female patient was admitted to hospital because of "gradual decline in visual acuity for more than 4 months". Ocular fundus examination revealed yellowish old hemorrhage in the macular area of both eyes, and fresh hemorrhage in the superficial retinal layer of the right eye. The patient had a history of bone marrow recurrence with previous acute myeloid leukemia (AML). After bone marrow transplantation in the Department of Hematology and Oncology, the patient's vision was improved and fundus hemorrhage was absorbed. Before the diagnosis of relapse of AML, the patient's vision had declined, but she did not go to the ophthalmology clinic in time. For leukemia patients, doctors are recommended to carry out adequate education for possible extramedullary symptoms and suggest regular ophthalmology consultations. If concomitant symptoms occur, it is suggested that multidisciplinary doctors should cooperate in diagnosis and treatment in order to obtain better therapeutic effect, restore visual function and improve the quality of life of patients.

Key words: acute myeloid leukemia (AML), recurrence, leukemic retinopathy, fundus hemorrhage

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