Abstract:

Objective To investigate the diagnostic value of color Doppler sonography in diagnosis of primary lung cancer, and explore the relationship between color Doppler sonography findings and histopathological types. Methods One hundred and twenty-six patients with primary lung cancer were examined by color Doppler sonography, and blood flow parameters of peak systolic velocity (Vp) and resistive index (RI) were measured. Comparison analysis was performed between those with adenocarcinoma and squamous cell carcinoma, between those with small cell carcinoma and non-small cell carcinoma, and between those with tumor diameter ≤50 mm and tumor diameter＞50 mm. Results There was no significant difference in Vp and RI between patients with squamous cell carcinoma and adenocarcinoma (P＞0.05). There was no significant difference in Vp between patients with nonsmall cell carcinoma and small cell carcinoma (P＞0.05), while there were significant differences in RI between patients with non-small cell carcinoma and small cell carcinoma (0.66±0.23 vs 0.83±0.21, P<0.05). There was no significant difference in Vp between patients with tumor diameter ≤50 mm and tumor diameter ＞50 mm (P＞0.05), while RI in patients with tumor diameter ＞50 mm was significantly lower than that in patients with tumor diameter ≤50 mm (0.63±0.21 vs 0.74±0.24, P<0.05). Conclusion There exists clinical value of Doppler sonography in differential diagnosis of small cell carcinoma and non-small cell carcinoma.

Key words: lung cancer, ultrasonography, Doppler, color