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Observation of cardiac and cerebral vascular endpoint events of families with familial hypertriglyceridemia

LIU Wei-juan1, HE Jin-chun1,2, HE Jin-xiang3, ZHOU Shan-shan1, ZHU Jin-hong2, YANG Yong-jian4   

  1. 1.the First Clinical Medicine College, 2.Clinical Laboratory, the First Hospital, 3.Department of Nuclear Medicine, the First Hospital, 4.Pharmacological College, Lanzhou University, Lanzhou 730000, China
  • Online:2014-12-28 Published:2014-12-30
  • Supported by:

    National Science and Technology Major Project of the Ministry of Science and Technology of China during the “10th Five-Year Plan”,2002DA711A028-17; Science and Technology Foundation Construction of Ministry of Education, 505015; Natural Science Foundation of Gansu Province,1308RJZA218

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Abstract:

Objective To investigate the effects of hypertriglyceridemia on cardiac and cerebral vascular endpoint events. Methods The data of familial hypertriglyceridemia in 10 years were collected and the occurrence of cardiac and cerebral vascular endpoint events of 2 family members was observed. Results In Family 1, Ⅲ 1 died of hemorrhagic stroke in the first year of study and Ⅲ 3 died of hemorrhagic stroke in the third year of study. Cardiac and cerebral vascular endpoint events did not occur among the rest family members. In Family 2, no cardiac and cerebral vascular endpoint events occurred. Conclusion For familial hypertriglyceridemia, pure hypertriglyceridemia does not cause cardiac and cerebral vascular endpoint events. The occurrence of cerebrovascular endpoint events increases with the presence of hypertension.

Key words: familial hypertriglyceridemia, family, cardiac and cerebral vascular events, follow-up