上海交通大学学报（医学版）

›› 2013, Vol. 33 ›› Issue (4): 520-.doi: 10.3969/j.issn.1674-8115.2013.04.030

• 短篇论著 • 上一篇    下一篇

钙泊三醇倍他米松软膏治疗非泛发型白癜风的疗效观察

周 隽, 李 剑, 傅雯雯   

  1. 复旦大学附属华山医院皮肤科, 上海 200040
  • 出版日期:2013-04-28 发布日期:2013-05-03
  • 通讯作者: 傅雯雯, 电子信箱: fuww@medmail.com.cn。
  • 作者简介:周 隽（1984—）, 男, 住院医师, 硕士； 电子信箱: zhoujun.huashan@gmail.com。

Effect of calcipotriol betamethasone ointment on treatment of non-generalized vitiligo

ZHOU Jun, LI Jian, FU Wen-wen   

  1. Department of Dermatology, Huashan Hospital, Fudan University, Shanghai 200040, China
  • Online:2013-04-28 Published:2013-05-03

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摘要：

目的 观察钙泊三醇倍他米松软膏治疗非泛发型白癜风的临床疗效和安全性。方法 51例非泛发型白癜风患者外用钙泊三醇倍他米松软膏，每日1次涂于患处，连续使用3个月，每月1次观察临床疗效及不良反应。结果 51例患者中，痊愈8例，显效21例，好转10例，无效12例；显效率56.86%（29/51，复色面积≥50%），有效率76.47%（39/51，复色面积≥10%）。结论 钙泊三醇倍他米松软膏治疗非泛发型白癜风安全、有效，不良反应小。

关键词: 白癜风, 治疗, 维生素D3, 钙泊三醇倍他米松

Abstract:

Objective To evaluate the therapeutic effect and safety of calcipotriol betamethasone ointment on the treatment of non-generalized vitiligo. Methods Calcipotriol betamethasone ointment was topically applied to the vitiliginous patches once daily in 51 patients with non-generalized vitiligo for 3 months, and the therapeutic effect and adverse effect were observed in each month. Results Of these 51 patients, 8 had complete repigmentation, 21 achieved excellent response, 10 experienced improvement, and the other 12 achieved almost no response. The excellent response rate was 56.86% (29/51, area of repigmentation≥50%), and the effective rate was 76.47% (39/51, area of repigmentation≥10%). Conclusion Calcipotriol betamethasone ointment is effective and safe in the treatment of vitiligo, with less adverse effect.

Key words: vitiligo, treatment, vitmin D3, calcipotriol betamethasone