肝门部胆管癌综合治疗的进展与争议

doi:10.3969/j.issn.1674-8115.2022.01.001

摘要/Abstract

摘要：

肝门部胆管癌早期诊断困难，预后较差，临床治疗存在诸多争议。目前，外科治疗仍是该病最主要的治疗方法。术前精准评估和充分准备，以及术中安全、有效、规范切除肿瘤是治疗成功的关键，以化学治疗（化疗）为主的综合治疗提高了患者的生存期。未来以肿瘤学理念为指导，包括手术、化疗、靶向、免疫和生物治疗多种模式的综合治疗是肝门部胆管癌治疗的发展趋势。

关键词: 肝门部胆管癌, 综合治疗, 外科手术, 减黄, 肝再生

Abstract:

Hilar cholangiocarcinoma is a tumor with a poor prognosis, which is difficult to diagnosis in the early stage and has caused lots of controversies in clinical treatment. At present, surgical resection provides the main possibility for cure. Precise evaluation and adequate preparation before surgery and safe, effective, standardized resection are the key methods to successful treatment. Comprehensive treatment based on chemotherapy improves the survival of patients. In the future, guided by concepts of oncology, comprehensive treatment of multiple modes, containing surgery, chemotherapy, targeted therapy, immune therapy and biological therapy, is the development trend of hilar cholangiocarcinoma treatment.

Key words: hilar cholangiocarcinoma, comprehensive treatment, surgical procedure, reducing jaundice, liver regeneration

中图分类号:

R735.8

陈炜, 刘颖斌. 肝门部胆管癌综合治疗的进展与争议[J]. 上海交通大学学报(医学版), 2022, 42(1): 1-8.

Wei CHEN, Yingbin LIU. Progress and controversy in comprehensive treatment of hilar cholangiocarcinoma[J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE), 2022, 42(1): 1-8.

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