上海交通大学学报（医学版）

›› 2010, Vol. 30 ›› Issue (12): 1481-.doi: 10.3969/j.issn.1674-8115.2010.12.008

• 专题报道（创伤医学） • 上一篇    下一篇

烧伤早期氧化损伤与抗氧化治疗

傅秀军, 方 勇   

  1. 上海交通大学 医学院附属第三人民医院烧伤整形科 创伤医学研究所, 上海 201900
  • 出版日期:2010-12-25 发布日期:2010-12-31
  • 通讯作者: 方 勇, 电子信箱: fang6242@hotmail.com。
  • 作者简介:傅秀军（1985—）, 男, 硕士生；电子信箱: fuxj84@yahoo.com.cn。

Oxidative injury and antioxidant therapy in early stage of burn

FU Xiu-jun, |FANG Yong   

  1. Department of Burns &|Plastic Surgery, The Third People's Hospital, Institute of Traumatic Medicine, Shanghai Jiaotong University School of Medicine, Shanghai 201900, China
  • Online:2010-12-25 Published:2010-12-31

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摘要：

严重烧伤早期由液体丢失及液体复苏而造成的缺血-再灌注损伤，以及应激而发生的神经、体液变化可使机体发生严重的氧化损伤，是导致多器官损伤的重要机制之一。文章就严重烧伤后活性氧对机体的氧化损伤及抗氧化治疗的研究进展作一综述。

关键词: 烧伤, 氧化损伤, 抗氧化治疗

Abstract:

In the early stage of severe burn, ischemia-reperfusion injury caused by fluid loss and fluid resuscitation and changes in nerve and body fluid caused by stress may lead to severe oxidative damage, which is one of the important mechanisms of multiple organ injury. The research progress of oxidative injury from reactive oxygen species and antioxidant therapy in the early stage of severe burn is reviewed in this paper.

Key words: burn, oxidative injury, antioxidant therapy