上海交通大学学报(医学版)

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焦虑障碍的谷氨酸学说研究进展

李梦瑶1,2,吴 彦2,杜亚松2   

  1. 1.上海交通大学医学院, 上海 200025; 2.上海交通大学 医学院附属精神卫生中心, 上海 200030
  • 出版日期:2014-04-28 发布日期:2014-05-13
  • 通讯作者: 吴 彦, 电子信箱: drwuyan@163.com; 杜亚松, 电子信箱: yasongdu@163.com。
  • 作者简介:李梦瑶(1989—), 女, 博士生; 电子信箱: miyali2@gmail.com。
  • 基金资助:

    上海市卫生局课题(2011303)

Advances of  role of glutamate in anxiety disorder

LI Meng-yao1,2, WU Yan2, DU Ya-song2   

  1. 1.Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; 2.Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
  • Online:2014-04-28 Published:2014-05-13
  • Supported by:

    Foundation of Shanghai Municipal Health Bureau, 2011303

摘要:

焦虑障碍是临床最常见的精神障碍之一。近年来,谷氨酸能神经递质在焦虑障碍发病机制和治疗中的作用逐渐受到人们的关注。本文就焦虑障碍的谷氨酸机制以及谷氨酸通路相关药物的临床研究进展作一综述。

关键词: 焦虑障碍, 谷氨酸, 兴奋性神经递质, 条件性恐惧

Abstract:

The anxiety disorder is one of the most common mental disorders in clinical practice. The role of glutamate neurotransmitters in the development and treatment of anxiety disorder is being increasingly studied in recent years. This paper reviews the progresses of the mechanism of glutamine on the anxiety disorder and the clinical researches on medication related to the glutamine pathway.

Key words: anxiety disorder, glutamine, excitatory neurotransmitter, conditional fear