上海交通大学学报（医学版）

上海交通大学学报（医学版） ›› 2019, Vol. 39 ›› Issue (4): 416-.doi: 10.3969/j.issn.1674-8115.2019.04.016

• 论著·临床研究 • 上一篇    下一篇

肾上腺皮质腺瘤和皮质增生结节的超声造影特征分析

李春晓，李　凡，白　敏，李　鑫，邵思惠   

  1. 上海交通大学附属第一人民医院超声科，上海 200080
  • 出版日期:2019-04-28 发布日期:2019-05-23
  • 通讯作者: 李　凡，电子信箱：medicineli@163.com。
  • 作者简介:李春晓（1989—），女，住院医师，博士生；电子信箱： lcx198910@126.com。

Analysis of contrast-enhanced ultrasound performance of adrenal cortical adenoma and cortical hyperplasia nodules

LI Chun-xiao, LI Fan, BAI Min, LI Xin, SHAO Si-hui   

  1. Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China
  • Online:2019-04-28 Published:2019-05-23

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摘要： 目的 ·探讨最大径 > 10 mm肾上腺皮质腺瘤和皮质增生结节的超声造影图像特征及其诊断价值。方法 ·回顾性分析经病理证实的 50例最大径 > 10 mm的肾上腺皮质腺瘤和 22例皮质增生结节，记录常规超声及超声造影图像特征，包括大小、边界等，造影剂到达时间，达峰时间，消退时间，增强程度 [低、高（等）增强]，增强方式（周边向中央增强、整体增强、无特殊形式）等。结果 · 2组结节在常规超声特征中未见显著差异。超声造影多参数分析结果表明，消退时间在 2组间的差异有统计学意义（ P0.002），其受试者工作特征（ receiver operating characteristic，ROC）曲线下面积为 0.694，诊断阈值 42 s的灵敏度为 75.7%,特异度为 53.3%。结论 ·肾上腺皮质腺瘤和皮质增生结节的超声造影图像未能提示显著鉴别诊断模式，但可为鉴别诊断提供一定信息。

关键词: 超声造影, 肾上腺肿瘤, 腺瘤

Abstract:

Objective · To explore the features of contrast-enhanced ultrasound (CEUS) image of adrenal cortical adenoma and cortical hyperplasia nodules (size greater than 10 mm) and its diagnostic value. Methods · Fifty cases of adrenal cortical adenoma and 22 cases of cortical hyperplasia nodules which were confirmedpathology were retrospectively analyzed. The conventional ultrasound and CEUS features were recorded, including the size,border,arrival time, peak time, wash-out time, enhancement degree [hypo, hyper (iso-)],enhancement pattern (peripheral to central,overall,and nonspecific), etc. Results · There was no significant differences between two groups among conventional ultrasonic features. Multi-parameters of CEUS images analysis results showed that the wash-out time of cortical adenomas were significantly longer than the cortical hyperplasia nodules (P0.002), the under area of the receiver operating characteristic (ROC) curve was 0.694, had the 75.7% sensitivity and 53.3% specificity with the cutoff of 42 s. Conclusion · There is no significant difference between the adrenal cortical adenoma and cortex hyperplasia nodules in CEUS pattern, but it still can provide certain information for differentiation. [Key words]contrast-enhanced ultrasound; adrenal tumor; adrenal cortical adenoma

Key words: contrast-enhanced ultrasound, adrenal tumor, adrenal cortical adenoma

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