医学院校临床研究水平提升的策略探讨

doi:10.3969/j.issn.1674-8115.2024.09.015

上海交通大学学报（医学版） ›› 2024, Vol. 44 ›› Issue (9): 1197-1204.doi: 10.3969/j.issn.1674-8115.2024.09.015

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医学院校临床研究水平提升的策略探讨

康力¹(), 王未¹, 冯铁男², 崔婷婷³, 王甦平¹^,⁴()

^1.上海交通大学医学院学科规划处，上海 200025
^2.上海交通大学医学院临床研究中心，上海 200025
^3.上海交通大学医学院图书馆，上海 200025
^4.上海交通大学中国医院发展研究院医学教育研究所，上海 200025

收稿日期:2024-06-29 接受日期:2024-07-31 出版日期:2024-09-28 发布日期:2024-10-09
通讯作者: 王甦平 E-mail:lkang@sjtu.edu.cn;wangsuping@shsmu.edu.cn
作者简介:康力（1980—），男，副研究员，博士；电子信箱：lkang@sjtu.edu.cn。
基金资助:
国家重点研发计划(2020YFC2006400)

Exploration of strategies for improving clinical research level in medical universities

KANG Li¹(), WANG Wei¹, FENG Tienan², CUI Tingting³, WANG Suping¹^,⁴()

^1.Office of Academic Planning and Development, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
^2.Clinical Research Institute, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
^3.Library, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
^4.China Hospital Development Institute, Shanghai Jiao Tong University, Shanghai 200025, China

Received:2024-06-29 Accepted:2024-07-31 Online:2024-09-28 Published:2024-10-09
Contact: WANG Suping E-mail:lkang@sjtu.edu.cn;wangsuping@shsmu.edu.cn
Supported by:
National Key Research and Development Program of China(2020YFC2006400)

摘要/Abstract

摘要：

目的·分析2015—2023年上海交通大学医学院（简称“交医”）高水平临床研究发展趋势及现状，并对交医临床研究水平的提升策略进行总结，旨在为医学院校推动高水平临床研究提供参考。方法·在Web of Science核心合集数据库中，检索发表时间为2015—2023年，以交医（含附属医院）作为第一作者所在机构发表的论文。利用一般描述性方法分析临床研究论文发表、临床试验注册、临床研究人才队伍、临床研究合作现况；运用文献计量方法对检索到的临床研究论文的国际合作、主题分布等进行可视化分析；对2015—2018年与2019—2023年两个时间段，交医在临床研究领域发文数、Q1区发文数、顶尖临床医学期刊发文数和专职科研人员数量方面的差异进行比较和分析。结果·2015—2023年，以交医为第一作者所在机构发表的临床研究论文共计9 468篇，年发文量呈逐年上升趋势；2015—2023年，交医临床研究Q1区发文数、顶尖临床医学期刊发文数、美国临床试验注册平台和中国临床试验注册中心注册的临床研究数、临床指南和专家共识发布数、专职科研队伍人数以及国家级人才新增人数均呈整体上升趋势；肿瘤、心脑血管疾病等重大慢性病为主要研究热点。临床研究论文中，1 308篇（13.82%）为国际合作论文，其中以美国（733篇）、澳大利亚（137篇）、英国（99篇）等发达国家/地区与交医合作论文居多。2019—2023年与2015—2018年相比，交医在临床研究论文数、Q1区发文数、顶尖临床医学期刊发文数和附属医院新增专职科研人数方面比较，均显著增加（均P<0.05）。结论·交医强化顶层设计，围绕重大疾病进行深入探索，以“平台-人才-方法学”为路径，构建了体系化、一体化和闭环式的临床研究水平提升模式，相继产出了一批高质量的临床研究成果。

关键词: 临床研究, 临床试验, 可视化分析, 聚类分析

Abstract:

Objective ·To analyze the development trend and current situation of high-level clinical research at Shanghai Jiao Tong University School of Medicine (SJTUSM) from 2015 to 2023, and to summarize the strategies for improving clinical research capability of SJTUSM, aiming to provide reference and inspiration for medical universities to promote high-level clinical research. Methods ·Papers published by first authors from SJTUSM or its affiliated hospitals during this period were retrieved in the Web of Science core collection database. General descriptive methods were used to quantify the number of clinical research papers, registered clinical trials, clinical research talent teams, and the current status of clinical research cooperation. Bibliometric methods were used to visualize the international collaboration and topic distribution of retrieved clinical research papers. The differences in the number of clinical research publications, Q1 publications, publications in top clinical medical journals, and full-time researchers between the periods of 2015?2018 and 2019?2023 were compared and analyzed. Results ·From 2015 to 2023, a total of 9 468 clinical research papers were published by SJTUSM or its affiliated hospitals as the first author′s institution, showing an increasing trend year by year. During this period, the number of Q1 publications of SJTUSM′s clinical research, publications in top clinical medical journals, clinical studies registered on the United States Clinical Trial Registry website, clinical studies registered on the Chinese Clinical Trial Registry website, clinical guidelines and expert consensus publications, full-time research team members, and newly added national-level talents all showed an overall upward trend. Tumors, cardiovascular and cerebrovascular diseases, major chronic diseases, and mental illnesses were the main research hotspots. A total of 1 308 papers (13.82%) were international collaborative papers. Developed countries/regions such as the United States (733 papers), Australia (137 papers), and the United Kingdom (99 papers) were closely cooperating with SJTUSM. From 2019 to 2023, there was a significant increase in the number of clinical research papers, Q1 publications, publications in top clinical medical journals, and newly added full-time research team members in affiliated hospitals compared to the period from 2015 to 2018 (all P<0.05). Conclusion ·SJTUSM has strengthened top-level design, conducted in-depth major diseases, and constructed a systematic, integrated and closed-loop model for enhancing clinical research level along the “platform-talent-methodology” pathway, resulting in a number of high-quality clinical research outcomes.

Key words: clinical research, clinical trial, visualization analysis, cluster analysis

中图分类号:

康力, 王未, 冯铁男, 崔婷婷, 王甦平. 医学院校临床研究水平提升的策略探讨[J]. 上海交通大学学报（医学版）, 2024, 44(9): 1197-1204.

KANG Li, WANG Wei, FENG Tienan, CUI Tingting, WANG Suping. Exploration of strategies for improving clinical research level in medical universities[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2024, 44(9): 1197-1204.

图/表 8

图1 2015—2023年交医SCI发文数

Fig 1 Number of SCI-indexed papers/clinical research papers of Shanghai Jiao Tong University School of Medicine (SJTUSM) from 2015 to 2023

图2 2015—2023年交医SCI论文JCR分区情况

Fig 2 JCR categorization of SCI-indexed papers published by SJTUSM from 2015 to 2023

图3 2015—2023年交医在顶尖临床医学期刊的论文发表情况

Fig 3 Publication status of top clinical research papers of SJTUSM from 2015 to 2023

图4 交医国际合作地区分布时间网络图谱

Fig 4 Time line network graph of international collaboration with SJTUSM

图5 交医临床研究论文主题词聚类

Fig 5 Clustering of theme words in clinical research papers of SJTUSM

图6 2015—2023年交医在美国临床试验注册平台注册的临床研究数量

Fig 6 Number of clinical trials registered on the United States Clinical Trial Registry by SJTUSM from 2015 to 2023

图7 2015—2023年交医在中国临床试验注册中心注册的临床研究数量

Fig 7 Number of clinical trials registered on the China Clinical Trial Registration Platform by SJTUSM from 2015 to 2023

图8 2015—2023年交医临床指南及专家共识发表情况

Fig 8 Clinical guidelines and expert consensus published by SJTUSM from 2015 to 2023

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医学院校临床研究水平提升的策略探讨

Exploration of strategies for improving clinical research level in medical universities

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