Objective To explore the responsibility sharing of relevant parts for the adverse drug reaction (ADR), modes of compensation financing, and the role of government in financing. Methods Two hundred and sixty pharmaceutical producing enterprises, 115 management authorities, and 125 drugs sales and users (medical institutions) were selected. The questionnaire was designed for the survey, which covered the ranking of responsibility sharing modes of ADR, methods of compensation financing, and the role of government in financing. The distributions of chosen items of each party were represented by the frequency and composition ratio. The chi square test was used to analyze the differences of distribution trends. Results There were 467 valid questionnaires and the valid rate was 93.4%. For the responsibility of damage sharing, pharmaceutical producing enterprises and management authorities should take the major responsibility, sales and medical institutions should take the minor responsibility, and victims took no responsibility. For the compensation financing, three parts all agreed that the most important methods were taxes, cash, and donations. For the role of government in financing, 96.2% of respondents believed that the government should invest, but their opinions towards the investment methods were different. And 55.3% of respondents believed that the government should invest proportionally. Conclusion When compensating the victims of ADR, pharmaceutical producing enterprises and management authorities should take the major responsibility, the major financing method is taxes, and the government should invest.