上海交通大学学报（医学版）

上海交通大学学报（医学版）

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大麻素受体1参与神经生长调控的研究进展

赵倩倩，韩洪秀   

  1. 上海交通大学 医学院附属第三人民医院病理科， 上海 201999
  • 出版日期:2015-08-28 发布日期:2015-09-30
  • 通讯作者: 韩洪秀, 电子信箱: hxhan2004@hotmail.com。
  • 作者简介:赵倩倩（1988—）， 女， 硕士生; 电子信箱: jdqqzhao@163.com。
  • 基金资助:

    上海市教委创新项目（13YZ038）；上海市科委自然科学基金（12ZR1417500）；上海市宝山区科委基金（12-E-4）

Research advances of the involvement of cannabinoid receptor 1 in the nerve growth

ZHAO Qian-qian, HAN Hong-xiu   

  1. Department of Pathology, the Third Peoples Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201999, China
  • Online:2015-08-28 Published:2015-09-30
  • Supported by:

    Innovation Project of Shanghai Municipal Education Committee, 13YZ038; Natural Science Foundation of Science and Technology Commission of Shanghai Municipality, 12ZR1417500; Foundation of Science and Technology Commission of Baoshan District of Shanghai, 12-E-4

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摘要：

大麻素系统紊乱可导致神经、代谢、免疫、心血管、消化系统疾病和癌症等疾病的发生, 因此，大麻素受体被认为是多种疾病的潜在治疗靶点。近年来，研究发现大麻素受体1参与中枢神经系统的生长发育过程。该文从大麻素受体1调控神经生长的分子机制方面进行综述。

关键词: 大麻素受体1, 神经生长, 分子机制

Abstract:

Disorder of cannabinoid systems leads to diseases of nervous system, metabolism, immune system, cardiovascular system，and digestive system and cancer. Thus, the cannabinoid receptor is considered as a potential therapeutic target for various diseases. Recent studies found the involvement of cannabinoid receptor 1 in the growth and development of central nervous system. This paper reviews the molecular mechanism of cannabinoid receptor 1 for regulating the growth of nerve.

Key words: cannabinoid receptor 1, nerve growth；molecular mechanism