上海交通大学学报（医学版）

上海交通大学学报（医学版） ›› 2019, Vol. 39 ›› Issue (6): 648-.doi: 10.3969/j.issn.1674-8115.2019.06.014

• 论著·公共卫生 • 上一篇    下一篇

孕妇对无创产前检测的认知、态度、意愿及需求调查

玛尔孜娅·玉苏甫江 1*，罗飞 1*，刘宇 2, 3，董媛媛 1，徐刚 1，周欣怡 1，金萍 1，李娜 1   

  1. 1. 上海交通大学公共卫生学院，上海 200025；2. 上海交通大学医学院附属新华医院小儿内分泌 /遗传科，上海 200092；3. 上海市儿科医学研究所，上海 200092
  • 出版日期:2019-06-28 发布日期:2019-07-26
  • 通讯作者: 金萍，电子信箱：jp493173620@126.com。李娜，电子信箱：nali@sjtu.edu.cn。为共同通信作者。
  • 作者简介:玛尔孜娅 ·玉苏甫江 (1996—)，女，维吾尔族，本科生；电子信箱： merziye27@163.com。罗飞 (1992—),女，硕士生；电子信箱： luofei0956@163. com。*为共同第一作者。
  • 基金资助:
    上海交通大学公共卫生学院卓越公共卫生人才培养项目；上海交通大学医学院地方高水平大学成果为导向本科生拔尖培养项目

Survey on cognition, attitude, willingness and demand for non-invasive prenatal testing among pregnant women

Maerziya YUSUFUJIANG1*, LUO Fei1*, LIU Yu2,3, DONG Yuan-yuan1, XU Gang1, ZHOU Xin-yi1, JIN Ping1, LI Na1   

  1. 1. Shanghai Jiao Tong University School of Public Health, Shanghai 200025, China; 2. Department of Pediatric Endocrinology/Genetics, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China; 3. Shanghai Institute for Pediatric Research, Shanghai 200092, China
  • Online:2019-06-28 Published:2019-07-26
  • Supported by:
    Excellent Public Health Talents Training Program of Shanghai Jiao Tong University School of Public Health; High-level Local Universities Outcome-oriented Top-notch Undergraduate Training Program of Shanghai Jiao Tong University School of Medicine）。

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摘要： 目的 ·了解孕妇对无创产前检测技术的认知程度、态度、意愿和需求。方法 ·选择上海交通大学医学院附属新华医院 318名血清学唐氏综合征筛查低风险孕妇及 534 名在上海多家医院经血清学唐氏综合征筛查发现为高风险并前往上海交通大学医学院附属新华医院无创产前检测门诊的孕妇作为研究对象。就 852名孕妇对无创产前检测技术的认知程度、态度、意愿和需求进行问卷调查。结果 ·回收问卷 760份，其中有效问卷共 728份，有效问卷率为 85.45%。孕妇对无创产前检测的认知达标率仅为 51.24%，但 83.10%的孕妇对无创产前检测的推广持积极态度。79.54%的孕妇认为在无创产前检测前提供的遗传咨询非常必要。结论 ·加强产前健康宣传教育、做好无创产前检测前的遗传咨询，可提高孕妇的认知程度，有助于合理利用无创产前检测。

关键词: 无创产前检测, 产前筛查, 产前诊断, 孕妇

Abstract:

Objective · To understand the cognition, attitude, willingness and demand for non-invasive prenatal testing (NIPT) of pregnant women. Methods · A total of 852 pregnant women were enrolled, including 318 pregnant women with low risk of Down syndrome screened in Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, and 534 pregnant women with high risk of Down syndrome screened in several hospitals in Shanghai who further went to Xinhua Hospital, Shanghai Jiao Tong University School of Medicine for NIPT to confirm the diagnosis of Down syndrome screening. The information about the cognition, attitude, willingness and demand for NIPT was collecteda standard questionnaire. Results · A total of 760 questionnaires were collected, of which 728 ones were valid, with an effective questionnaire rate of 85.45%. The proportion of pregnant women with ideal cognition level was 51.24%. However, 83.10% of pregnant women held a positive attitude towards the promotion of NIPT. There were 79.54% of pregnant women considering it necessary to provide genetic counseling before NIPT. Conclusion · It is of great significance to strengthen the prenatal propaganda and education and pre-test genetic counseling so as to improve the cognitive level of pregnant women and make rational of NIPT.

Key words: non-invasive prenatal testing (NIPT), prenatal screening, prenatal diagnosis, pregnant women

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